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All animal experiments were approved by and conducted in compliance with Institutional Animal Care and Use Committee (IACUC) of the University of Colorado Anschutz Medical Campus

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Future research must prioritize longitudinal human studies to validate causal links and identify robust diagnostic biomarkers detectable in oral samples

52 For an ideal assessment of the type, quantity, and frequency of food intake, real-time monitoring would be preferable over methods such as 24-hour dietary recalls or short-term measurements of food consumption

Individuals with Vitamin B12 deficiency may notice improvement as deficiency is corrected